Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31199208 | 0.95 | TSHR (0.74) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976282 | 0.95 | HTT (0.82) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976269 | 0.93 | ALDH1A1 (0.77) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976290 | 0.92 | ALDH1A1 (0.72) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976279 | 0.90 | ALDH1A1 (0.78) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976373 | 0.88 | L3MBTL1 (0.77) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976425 | 0.88 | TSHR (0.68) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976262 | 0.87 | HTT (0.70) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976337 | 0.87 | KMT2A (0.90) | HTTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL30976523 | 0.87 | NPSR1 (0.81) | HTTTSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |