Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976418 | 0.94 | MEN1 (0.51) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30976428 | 0.86 | MEN1 (0.55) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30976384 | 0.82 | MEN1 (0.53) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30976325 | 0.80 | LMNA (0.54) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL30976499 | 0.74 | LMNA (0.56) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL30976411 | 0.72 | TP53 (0.56) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30976440 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28322333 | 0.70 | MAPT (0.69) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL30976463 | 0.70 | LMNA (0.58) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL30976302 | 0.70 | LMNA (0.52) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |