SCHEMBL30978207

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	17/20	0.60

▸	PTH1R	Q03431	2/20	0.57

▸	RXFP1	Q9HBX9	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29663916	0.91	PTH1R (0.59)	GLP1RPTH1RRXFP1
SCHEMBL30874405	0.90	RXFP1 (0.64)	GLP1RPTH1RRXFP1
SCHEMBL2469583	0.90	RXFP1 (0.61)	GLP1RPTH1RRXFP1
SCHEMBL29760958	0.87	KISS1R (0.57)	GLP1RPTH1RRXFP1
SCHEMBL31093453	0.87	RXFP1 (0.69)	GLP1RPTH1RRXFP1
SCHEMBL29462132	0.87	RXFP1 (0.70)	GLP1RPTH1RRXFP1
SCHEMBL30183270	0.87	RXFP1 (0.70)	GLP1RPTH1RRXFP1
SCHEMBL30629650	0.86	PTH1R (0.56)	PTH1R
SCHEMBL29493518	0.86	PTH1R (0.56)	PTH1R
SCHEMBL29555515	0.86	GHSR (0.64)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-109996557-B	Novel compounds as peptide GLP 1/glucagon/GIP receptor agonists	赛诺菲	2024-05-03	—	—	CN	disclosed