Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657830 | 0.70 | ALDH1A1 (0.47) | — | |
| SCHEMBL30449933 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL29181950 | 0.65 | KDM5A (0.32) | — | |
| SCHEMBL11037870 | 0.65 | — | — | |
| SCHEMBL5815964 | 0.65 | — | — | |
| SCHEMBL17334174 | 0.64 | CFTR (0.33) | — | |
| SCHEMBL28961166 | 0.63 | POLB (0.35) | — | |
| SCHEMBL29152644 | 0.63 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL28326518 | 0.63 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL27518236 | 0.63 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221669-A | Derivatives as DNA polymerase Theta inhibitors | 艾立康药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |