Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657830 | 0.98 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL28673249 | 0.75 | KMT2A (0.62) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL29181950 | 0.73 | KDM5A (0.32) | ALDH1A1TSHRHPGDMAPK1HSD17B10 | |
| SCHEMBL30473912 | 0.73 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL29181947 | 0.71 | FAAH (0.40) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL31111632 | 0.69 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL2050164 | 0.69 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL30978268 | 0.69 | CHRNB2 (0.30) | — | |
| SCHEMBL28961166 | 0.68 | POLB (0.35) | POLBMAPTLMNAHPGDHSD17B10 | |
| SCHEMBL29152644 | 0.68 | SMN1; SMN2 (0.33) | ALDH1A1POLBSMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249554-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2023-06-09 | — | — | CN | disclosed |