Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5471125 | 0.97 | MEN1 (0.41) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Bicarbonate SCHEMBL30978285 | 0.94 | MEN1 (0.32) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Hydrogen Peroxide SCHEMBL2572903 | 0.90 | MEN1 (0.47) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Hydrogen Peroxide SCHEMBL3145484 | 0.90 | MEN1 (0.47) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Oxalic Acid SCHEMBL27870285 | 0.88 | MEN1 (0.39) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| SCHEMBL31508284 | 0.87 | TSHR (0.40) | MEN1ALDH1A1TSHRKMT2A | |
| Bicarbonate SCHEMBL8405677 | 0.85 | CA4 (0.39) | MEN1ALDH1A1TSHRKMT2ACA1 | |
| Acetic Acid SCHEMBL29148901 | 0.85 | FFAR3 (0.41) | MEN1ALDH1A1TSHRKMT2ACA1 | |
| Bicarbonate SCHEMBL25247505 | 0.84 | CA2 (0.50) | MEN1ALDH1A1TSHRKMT2ACA2 | |
| Bicarbonate SCHEMBL28163394 | 0.84 | CA2 (0.50) | MEN1ALDH1A1TSHRKMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165145-A | Synthesis method of low molecular weight vinyl-terminated fluorine-containing polymer | 沈阳化工大学 | 2024-06-11 | — | — | CN | disclosed |