Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097856 | 1.00 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3090802 | 0.95 | LMNA (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3090812 | 0.95 | LMNA (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2989611 | 0.86 | GSR (0.44) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL1950999 | 0.86 | GSR (0.44) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3102683 | 0.85 | LMNA (0.35) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3102709 | 0.85 | LMNA (0.35) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3098014 | 0.83 | LMNA (0.42) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3103112 | 0.81 | OTC (0.37) | — | |
| SCHEMBL3098040 | 0.81 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |