Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102683 | 1.00 | LMNA (0.35) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3094189 | 0.95 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3094211 | 0.95 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2993454 | 0.87 | GSR (0.43) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2993448 | 0.87 | GSR (0.43) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3097856 | 0.85 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3097884 | 0.85 | LMNA (0.36) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2991842 | 0.81 | CPB2 (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2991853 | 0.81 | CPB2 (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3087403 | 0.80 | OTC (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |