Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987512 | 0.87 | KDM6B (0.53) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL2987516 | 0.87 | KDM6B (0.53) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL3106082 | 0.84 | SLC7A5 (0.42) | SLC7A5ESR1SLC6A2CA1CA2 | |
| SCHEMBL3106093 | 0.84 | SLC7A5 (0.42) | SLC7A5ESR1SLC6A2CA1CA2 | |
| SCHEMBL3091879 | 0.80 | LAP3 (0.51) | PTGS1SLC7A5ALDH1A1POLBCYP1A2 | |
| SCHEMBL3091871 | 0.80 | LAP3 (0.51) | PTGS1SLC7A5ALDH1A1POLBCYP1A2 | |
| SCHEMBL3098872 | 0.75 | ALOX15 (0.57) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL27997874 | 0.72 | LAP3 (0.58) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| SCHEMBL2992444 | 0.71 | SLC7A5 (0.47) | SLC7A5MEN1ESR1KMT2APOLB | |
| SCHEMBL2992448 | 0.71 | SLC7A5 (0.47) | SLC7A5MEN1ESR1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |