Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979073 | 0.85 | ABCG2 (0.41) | CACNA1BAPBA1NPSR1ABCG2EGFR | |
| SCHEMBL30979042 | 0.85 | MAPT (0.50) | NPSR1ABCG2EGFRHTTTP53 | |
| SCHEMBL30979071 | 0.85 | EPHX2 (0.51) | CACNA1BAPBA1NPSR1EGFRTP53 | |
| SCHEMBL30979013 | 0.83 | TP53 (0.43) | ABCG2EGFRTP53MAPTKDR | |
| SCHEMBL30978990 | 0.80 | TP53 (0.43) | ABCG2EGFRTP53MAPTKDR | |
| SCHEMBL30979119 | 0.79 | LATS1 (0.43) | ABCG2TP53MAPTKDRPOLB | |
| SCHEMBL30979016 | 0.78 | NPY5R (0.47) | NPSR1ABCG2HTTTP53MAPT | |
| SCHEMBL30979050 | 0.78 | EGFR (0.41) | ABCG2EGFRTP53MAPTKMT2A | |
| SCHEMBL30979053 | 0.77 | ALDH1A1 (0.44) | TSHRTP53MAPTKDRKMT2A | |
| SCHEMBL30978938 | 0.77 | PDE5A (0.46) | ABCG2TSHRHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |