SCHEMBL3097928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3082753	0.81	HRH3 (0.40)	PDE4APDE4BPDE4CPDE4DHRH3
	SCHEMBL3089672	0.80	SMN1; SMN2 (0.54)	PDE4APDE4BPDE4CPDE4DALDH1A1
	SCHEMBL3097922	0.79	HRH3 (0.69)	PDE4APDE4BPDE4CPDE4DHRH3
	SCHEMBL3087258	0.76	HRH3 (0.56)	HRH3
	SCHEMBL3089521	0.76	HRH3 (0.52)	HRH3
	SCHEMBL3082605	0.76	HRH3 (0.59)	HRH3ALDH1A1NPC1RAB9A
	SCHEMBL3082442	0.73	TSHR (0.44)	HRH3ALDH1A1NPC1LMNAMAPT
	SCHEMBL1787356	0.72	ALDH1A1 (0.57)	SRD5A1SRD5A2ALDH1A1MAPT
	SCHEMBL1789887	0.72	HDAC6 (0.43)	OPRD1OPRK1SRD5A1SRD5A2OPRM1
	SCHEMBL1707162	0.72	HRH3 (0.66)	HRH3OPRD1OPRK1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.