Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511380 | 0.83 | EGLN1 (0.43) | EGLN1PARP4PARP1PARP2GRIN2D | |
| SCHEMBL25309684 | 0.83 | EGLN1 (0.43) | EGLN1PARP4PARP1PARP2GRIN2D | |
| SCHEMBL31424794 | 0.83 | LMNA (0.42) | EGLN1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14765195 | 0.81 | ALDH1A1 (0.45) | PARP2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30979307 | 0.79 | GRIN2D (0.36) | PARP4PARP1PARP2GRIN2DGRIN3B | |
| SCHEMBL1144583 | 0.78 | SMN1; SMN2 (0.50) | EGLN1PARP4PARP1PARP2CYP1A2 | |
| SCHEMBL30888946 | 0.78 | SMN1; SMN2 (0.50) | EGLN1PARP4PARP1PARP2CYP1A2 | |
| SCHEMBL31424683 | 0.77 | MAPT (0.40) | PARP4PARP1PARP2IGF1REGFR | |
| SCHEMBL31424573 | 0.77 | PDE5A (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31424773 | 0.76 | HTT (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076597-A | Azaquinolinone derivative, preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |