SCHEMBL30979490

SCHEMBL30979490

CSCc1ccc2nccc(Cl)c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1B Q9Y463 1/20 0.38
NR4A2 P43354 1/20 0.37
MET P08581 1/20 0.36
AXL P30530 1/20 0.35
PRKCI P41743 1/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
CYP2C19 P33261 3/20 0.34
CYP3A4 P08684 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HIF1A Q16665 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
PDE5A O76074 1/20 0.34
SLC22A12 Q96S37 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27469333 1.00 DYRK1B (0.38) DYRK1BNR4A2METAXLPRKCI
SCHEMBL14690592 0.81 NOS3 (0.43) DYRK1BNR4A2AXLPRKCINOS3
SCHEMBL27469327 0.81 SLC22A12 (0.39) NOS3NOS1NOS2CYP1A2CYP2C9
SCHEMBL2882741 0.78 RECQL (0.52) DYRK1BNR4A2AXLPRKCICYP2C19
SCHEMBL7219125 0.78 DYRK1B (0.40) DYRK1BNR4A2AXLPRKCICYP2C19
SCHEMBL16247958 0.77 SLC22A12 (0.48) DYRK1BNR4A2AXLPRKCICYP2C19
SCHEMBL30523311 0.75 TAAR1 (0.50) DYRK1BNR4A2AXLPRKCIKDM4E
SCHEMBL4015831 0.75 SMN1; SMN2 (0.44) DYRK1BNR4A2METAXLPRKCI
SCHEMBL30979525 0.75 SMN1; SMN2 (0.44) DYRK1BNR4A2METAXLPRKCI
SCHEMBL24368224 0.74 PIK3CG (0.39) DYRK1BNR4A2AXLPRKCICYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622970-A1 INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-10-01 EP disclosed
WO-2024112854-A1 INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2024-05-30 WO disclosed