Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657341 | 0.81 | TRPA1 (0.47) | SLC22A12NOS3NOS1NOS2SMN1; SMN2 | |
| SCHEMBL27469333 | 0.81 | DYRK1B (0.38) | SLC22A12NOS3NOS1NOS2HTR1A | |
| SCHEMBL30979490 | 0.81 | DYRK1B (0.38) | SLC22A12NOS3NOS1NOS2HTR1A | |
| SCHEMBL2588801 | 0.75 | SMN1; SMN2 (0.44) | SLC22A12CYP1A2SMN1; SMN2HSD17B10MAPKAPK2 | |
| SCHEMBL24368246 | 0.74 | KDM4E (0.51) | SLC22A12HSD17B10LMNA | |
| SCHEMBL3862227 | 0.74 | IDH1 (0.51) | SLC22A12CDK8 | |
| SCHEMBL27907349 | 0.74 | SLC22A12 (0.39) | SLC22A12HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16247960 | 0.72 | SLC22A12 (0.56) | SLC22A12CYP19A1MAPKAPK2AKT1PIK3CA | |
| SCHEMBL21465994 | 0.72 | NOS3 (0.41) | NOS3NOS1NOS2MIFCYP1A2 | |
| SCHEMBL5539379 | 0.72 | HTR1A (0.54) | SLC22A12NOS3NOS1NOS2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |