Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165658 | 0.83 | HRH3 (0.53) | NPC1MAPTHRH3LMNAALDH1A1 | |
| SCHEMBL23859943 | 0.83 | HRH3 (0.53) | NPC1MAPTHRH3LMNAALDH1A1 | |
| SCHEMBL23867468 | 0.82 | HRH3 (0.45) | SLC2A1MAPTHRH3KMT2AMEN1 | |
| SCHEMBL30234700 | 0.81 | HRH3 (0.47) | SLC2A1HTR1APOLBMAPTHRH3 | |
| SCHEMBL23867470 | 0.81 | HRH3 (0.44) | SLC2A1MAPTHRH3KMT2AMEN1 | |
| SCHEMBL23867472 | 0.81 | HRH3 (0.48) | SLC2A1POLBMAPTHRH3KMT2A | |
| SCHEMBL23867524 | 0.80 | HCRTR1 (0.52) | SLC2A1MAPTHRH3KMT2AMEN1 | |
| SCHEMBL23867509 | 0.80 | CCNE1 (0.50) | MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL23867523 | 0.80 | SLC2A1 (0.49) | SLC2A1MAPTLMNAMAPK1ALDH1A1 | |
| SCHEMBL23867473 | 0.80 | HCRTR1 (0.53) | SLC2A1HTR1AMAPK1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118338898-A | Small molecule inhibitors of oncogenic CHD1L with preclinical anti-colorectal cancer activity | 科罗拉多州立大学董事会（法人团体） | 2024-07-12 | — | — | CN | disclosed |