Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.49 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 2/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979651 | 0.80 | SLC2A1 (0.51) | SLC2A1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL31094238 | 0.79 | SLC2A1 (0.50) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31094224 | 0.79 | SLC2A1 (0.51) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23859943 | 0.78 | HRH3 (0.53) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30165658 | 0.78 | HRH3 (0.53) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL23859942 | 0.78 | POLB (0.55) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23867524 | 0.77 | HCRTR1 (0.52) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23867649 | 0.77 | ALDH1A1 (0.52) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31094227 | 0.76 | SLC2A1 (0.44) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23867468 | 0.76 | HRH3 (0.45) | SLC2A1LMNAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055763-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTRAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |