Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 1.00 |
| ▸ | NQO1 | P15559 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CLK1 | P49759 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297329 | 1.00 | HPGDS (1.00) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| SCHEMBL2201992 | 1.00 | HPGDS (1.00) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| SCHEMBL7504247 | 0.89 | HPGDS (0.81) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| SCHEMBL6990269 | 0.87 | HPGDS (0.77) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL29902485 | 0.86 | HPGDS (0.75) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| SCHEMBL4964483 | 0.84 | HPGDS (0.73) | HPGDSNQO1PDGFRBPDGFRAKDM4E | |
| SCHEMBL29624688 | 0.84 | HPGDS (0.73) | HPGDSNQO1PDGFRBPDGFRAKDM4E | |
| SCHEMBL27555688 | 0.84 | HPGDS (0.72) | HPGDSNQO1EGFRPDGFRBPDGFRA | |
| SCHEMBL17327692 | 0.82 | HPGDS (0.69) | HPGDSNQO1PDGFRBPDGFRAKDM4E | |
| SCHEMBL28808959 | 0.79 | HPGDS (0.65) | HPGDSNQO1EGFRPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | ERBB2, EGFR, ERBB3 | HPGDS 1648/4885NQO1 667/4885EGFR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.