Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624688 | 1.00 | HPGDS (0.73) | HPGDSGLAMAPTNPC1ALDH1A1 | |
| SCHEMBL17327692 | 0.88 | HPGDS (0.69) | HPGDSMAPTNPC1ALDH1A1HSD17B10 | |
| SCHEMBL28120216 | 0.88 | HPGDS (0.56) | HPGDSGLAMAPTNPC1ALDH1A1 | |
| SCHEMBL31297329 | 0.84 | HPGDS (1.00) | HPGDSGLAMAPTALDH1A1HSD17B10 | |
| SCHEMBL30979880 | 0.84 | HPGDS (1.00) | HPGDSGLAMAPTALDH1A1HSD17B10 | |
| SCHEMBL2201992 | 0.84 | HPGDS (1.00) | HPGDSGLAMAPTALDH1A1HSD17B10 | |
| SCHEMBL27555688 | 0.84 | HPGDS (0.72) | HPGDSMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7565814 | 0.80 | SLC6A2 (0.56) | HPGDSGLAMAPTNPC1ALDH1A1 | |
| SCHEMBL17316167 | 0.80 | HPGDS (0.62) | HPGDSNPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL28878233 | 0.80 | NQO1 (0.53) | HPGDSGLAMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357854-A | A kind of preparation method of linatinib | 江苏创诺制药有限公司 | 2019-10-22 | — | — | CN | claimed |
| US-12194031-B2 | Compounds for use in regulating follicle maturation | AARHUS UNIVERSITET (DK) | 2025-01-14 | — | — | US | disclosed |
| US-20230285375-A1 | COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION | AARHUS UNIVERSITET (DK) | 2023-09-14 | — | — | US | disclosed |
| US-11666561-B2 | Compounds for use in regulating follicle maturation | AARHUS UNIVERSITET (DK) | 2023-06-06 | — | — | US | disclosed |
| CN-110357855-A | A kind of linatinib hydrochloride Form and preparation method thereof | 江苏创诺制药有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110357854-A | A kind of preparation method of linatinib | 江苏创诺制药有限公司 | 2019-10-22 | — | — | CN | disclosed |
| EP-1888529-A2 | 3-CYANOQUINOLINE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | Wyeth (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006124692-A2 | 3-CYANOQUINOLINE INHIBITORS OF TPL2 KINASE AND METHODS OF MAKING AND USING THE SAME | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| EP-1263503-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001068186-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |