SCHEMBL30980418

SCHEMBL30980418

CC(C)(C)OC(=O)N[C@@H](CF)CBr

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
AAK1 Q2M2I8 4/20 0.42
CTSK P43235 9/20 0.41
CYP2D6 P10635 1/20 0.41
ATM Q13315 1/20 0.40
APLNR P35414 1/20 0.39
CTSS P25774 4/20 0.39
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24741997 0.84 CA1 (0.46) CA1CA2CA7AAK1CTSK
SCHEMBL26660843 0.84 CA1 (0.46) CA1CA2CA7AAK1CTSK
SCHEMBL26660847 0.84 CA1 (0.46) CA1CA2CA7AAK1CTSK
SCHEMBL10464366 0.84 CTSK (0.46) CA1CA2CA7AAK1CTSK
SCHEMBL31030111 0.83 CA1 (0.42) CA1CA2CA7AAK1CTSK
SCHEMBL22806217 0.82 CA1 (0.45) CA1CA2CA7AAK1CTSK
SCHEMBL8561571 0.82 CA1 (0.53) CA1CA2CA7AAK1CTSK
SCHEMBL8560322 0.82 CA1 (0.53) CA1CA2CA7AAK1CTSK
SCHEMBL20583942 0.81 CA1 (0.44) CA1CA2CA7AAK1CTSK
SCHEMBL11127933 0.81 CA1 (0.44) CA1CA2CA7CTSKCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651948-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651946-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651951-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651953-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651945-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651947-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024155837-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
WO-2024155847-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
WO-2024155840-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
WO-2024155836-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
WO-2024155846-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
WO-2024155838-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed