Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393065 | 0.90 | LMNA (0.54) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL16393027 | 0.90 | LMNA (0.54) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL7616209 | 0.88 | LMNA (0.53) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL30721980 | 0.88 | LMNA (0.45) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL16392999 | 0.86 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL28694159 | 0.86 | LMNA (0.53) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL31538817 | 0.85 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL22899114 | 0.85 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL18349732 | 0.85 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1NR3C1 | |
| SCHEMBL26986927 | 0.84 | NR3C1 (0.59) | NR3C1FYNADRA2AADORA3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |