Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980746 | 0.89 | TP53 (0.44) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL30980634 | 0.85 | TP53 (0.41) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL31734181 | 0.84 | TP53 (0.52) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL30980533 | 0.83 | TP53 (0.52) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL31078995 | 0.82 | LMNA (0.43) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL13296098 | 0.81 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL30980639 | 0.80 | TP53 (0.41) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL30980528 | 0.80 | TP53 (0.41) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL24378386 | 0.79 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15514084 | 0.79 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025035040-A1 | LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES | LYCIA THERAPEUTICS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |