SCHEMBL30980664

SCHEMBL30980664

CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1CCCOCCOCCNC(=O)NCCCC(C)(CCCNC(=O)NCCOCCOCCC[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O)NC(=O)NCCOCCOCCOCCNC(=O)OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ HRAS P01112 1/20 0.39
▸ HEXA P06865 1/20 0.36
▸ HTT P42858 1/20 0.35
▸ MAPT P10636 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ FOLH1 Q04609 1/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980659 0.94 LMNA (0.41) LMNASMN1; SMN2HRASHEXAHTT
SCHEMBL30980620 0.91 HRAS (0.39) LMNASMN1; SMN2HRASHEXA
SCHEMBL31078937 0.85 HRAS (0.38) LMNASMN1; SMN2HRASHEXA
SCHEMBL30980568 0.84 MAPK1 (0.38) SMN1; SMN2MEN1KMT2A
SCHEMBL30980607 0.81 MDK (0.40) LMNASMN1; SMN2HRASHEXA
SCHEMBL30980624 0.79 MAPK1 (0.52) LMNASMN1; SMN2HRASMEN1KMT2A
SCHEMBL30980682 0.79 CA1 (0.35) —
SCHEMBL30980709 0.79 MAPK1 (0.41) SMN1; SMN2MEN1KMT2A
SCHEMBL24239904 0.78 LMNA (0.52) LMNASMN1; SMN2HRASMEN1KMT2A
SCHEMBL30980649 0.76 MAPK1 (0.43) SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
WO-2025035040-A1 LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES LYCIA THERAPEUTICS, INC. (US) 2025-02-13 — — WO disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 — — WO disclosed
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