SCHEMBL30980730

SCHEMBL30980730

CC(=O)N[C@@H]1[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](COCc2ccccc2)O[C@@H]1c1cn(CCOCCOCCN)nn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 2/20 0.56
▸ MDM2 Q00987 2/20 0.56
▸ MDM4 O15151 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ HSP90AB1 P08238 1/20 0.50
▸ PTPN1 P18031 14/20 0.44
▸ PTPN2 P17706 10/20 0.44
▸ CDC25B P30305 11/20 0.42
▸ PTPN6 P29350 5/20 0.41
▸ PTPN11 Q06124 5/20 0.41
▸ BCHE P06276 1/20 0.41
▸ CDC25A P30304 2/20 0.40
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ SSTR4 P31391 2/20 0.38
▸ SSTR1 P30872 1/20 0.38
▸ SSTR2 P30874 1/20 0.38
▸ SSTR3 P32745 1/20 0.38
▸ SSTR5 P35346 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980721 0.77 LGALS3 (0.49) CA1CA2CA9
SCHEMBL30980723 0.76 TP53 (0.45) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL13296082 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL15516519 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL5840927 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL24378386 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL13296098 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL5840884 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL15514084 0.73 TP53 (0.55) TP53MDM2MDM4HSP90AA1HSP90AB1
SCHEMBL13296075 0.73 TP53 (0.57) TP53MDM2MDM4HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 — — WO disclosed
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