SCHEMBL30980923

SCHEMBL30980923

CC(C)(C)c1ccc(Nc2ccc(-c3ccccc3)cc2)c(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
ABCG2 Q9UNQ0 2/20 0.42
PTGER4 P35408 1/20 0.40
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 1/20 0.40
PLA2G1B P04054 1/20 0.40
NFKB1 P19838 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
HSD17B2 P37059 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26485726 1.00 AKR1C3 (0.42) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1
SCHEMBL23118189 0.95 AKR1C3 (0.46) AKR1C3AKR1C2ABCG2ALDH1A1L3MBTL1
SCHEMBL30503054 0.95 AKR1C3 (0.46) AKR1C3AKR1C2ABCG2ALDH1A1L3MBTL1
SCHEMBL24137226 0.94 NR3C2 (0.40) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1
SCHEMBL30812369 0.94 RXRA (0.41) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1
SCHEMBL27199078 0.94 RXRA (0.41) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1
SCHEMBL30561839 0.94 ALDH1A1 (0.44) AKR1C3AKR1C2ABCG2ALDH1A1L3MBTL1
SCHEMBL25120147 0.94 ALDH1A1 (0.44) AKR1C3AKR1C2ABCG2ALDH1A1L3MBTL1
SCHEMBL31013596 0.92 HSD17B2 (0.44) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1
SCHEMBL31013592 0.92 HSD17B2 (0.44) AKR1C3AKR1C2ABCG2PTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307567-A Method for producing heterocyclic compound, light-emitting device, and electronic apparatus and electronic device including the light-emitting device 三星显示有限公司 2024-07-09 CN disclosed