Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432010 | 0.87 | DRD2 (0.65) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL11562405 | 0.80 | DRD2 (0.61) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL3931858 | 0.80 | DRD2 (0.61) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL15205752 | 0.80 | EGFR (0.46) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL15205751 | 0.80 | EGFR (0.46) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL1012326 | 0.80 | DRD2 (0.57) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL6211429 | 0.79 | OPRM1 (0.63) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL3730443 | 0.78 | DRD2 (0.72) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL11077040 | 0.78 | DRD2 (0.58) | DRD2SLC6A4OPRM1OPRL1PKM | |
| SCHEMBL3290233 | 0.76 | DRD2 (0.57) | DRD2SLC6A4OPRM1OPRL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |