Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.63 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199173 | 0.97 | DDB1 (0.64) | DDB1CRBNGPR119TGFBR1ALDH1A1 | |
| SCHEMBL25845750 | 0.93 | DDB1 (0.65) | DDB1CRBNGPR119TGFBR1ALDH1A1 | |
| SCHEMBL30981083 | 0.92 | DDB1 (0.58) | DDB1CRBNGPR119TGFBR1 | |
| SCHEMBL30981210 | 0.92 | DDB1 (0.54) | DDB1CRBNGPR119TGFBR1 | |
| SCHEMBL30981048 | 0.91 | DDB1 (0.61) | DDB1CRBNGPR119TGFBR1ALDH1A1 | |
| SCHEMBL30981483 | 0.91 | DDB1 (0.56) | DDB1CRBNGPR119 | |
| SCHEMBL30120110 | 0.91 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL20595430 | 0.91 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL20595405 | 0.91 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL29554651 | 0.90 | DDB1 (0.68) | DDB1CRBNGPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |