Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 9/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.64 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30981069 | 0.97 | DDB1 (0.63) | DDB1CRBNTGFBR1GPR119ALDH1A1 | |
| SCHEMBL25845750 | 0.92 | DDB1 (0.65) | DDB1CRBNTGFBR1GPR119ALDH1A1 | |
| SCHEMBL30120110 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL20595430 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL20595405 | 0.92 | DDB1 (0.74) | DDB1CRBNGPR119ALDH1A1LMNA | |
| SCHEMBL30981048 | 0.92 | DDB1 (0.61) | DDB1CRBNTGFBR1GPR119ALDH1A1 | |
| SCHEMBL25631844 | 0.91 | DDB1 (0.57) | DDB1CRBNTGFBR1GPR119 | |
| SCHEMBL31701423 | 0.91 | DDB1 (0.57) | DDB1CRBNTGFBR1GPR119 | |
| SCHEMBL30981083 | 0.90 | DDB1 (0.58) | DDB1CRBNTGFBR1GPR119 | |
| SCHEMBL27178787 | 0.90 | DDB1 (0.66) | DDB1CRBNGPR119ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736187-B | Proteolysis targeting chimeric and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117736187-A | Proteolysis targeting chimeric and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2024-03-22 | — | — | CN | disclosed |