Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 13/20 | 0.35 |
| ▸ | NPY1R | P25929 | 8/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991927 | 0.90 | OTC (0.41) | OTCNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL2992625 | 0.87 | OTC (0.37) | OTCNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL3091575 | 0.87 | OTC (0.37) | OTCNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22279914 | 0.84 | ALOX15 (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL3097987 | 0.82 | ALOX15 (0.36) | OTCNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL3100443 | 0.81 | LMNA (0.44) | CYP1A2ALDH1A1TDP1 | |
| SCHEMBL3095512 | 0.80 | LMNA (0.42) | ALDH1A1TDP1 | |
| SCHEMBL10727007 | 0.79 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL1388278 | 0.78 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL8120411 | 0.78 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |