SCHEMBL30982000

SCHEMBL30982000

CC1(C)OB(c2cc(Cl)c(Cl)cc2N)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
CD44 P16070 1/20 0.34
JAK2 O60674 1/20 0.32
BTK Q06187 1/20 0.32
LPL P06858 4/20 0.32
LIPG Q9Y5X9 4/20 0.32
P2RX7 Q99572 1/20 0.32
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27409909 1.00 GAA (0.36) GAACD44JAK2BTKLPL
SCHEMBL18350270 0.86 EGFR (0.36) GAACD44JAK2BTKLPL
SCHEMBL22636705 0.82 PGK1 (0.31)
SCHEMBL5504723 0.80 CD44 (0.39) GAACD44JAK2BTKCYP3A4
SCHEMBL20268037 0.80 CD44 (0.39) GAACD44JAK2BTKCYP3A4
SCHEMBL23974414 0.79 GAA (0.39) GAAJAK2BTKLPLLIPG
SCHEMBL44671 0.79 CYP3A4 (0.43) GAALPLLIPGCYP3A4TSHR
SCHEMBL29396514 0.79 CYP3A4 (0.43) GAALPLLIPGCYP3A4TSHR
SCHEMBL29885660 0.79 GAA (0.39) GAAJAK2BTKLPLLIPG
SCHEMBL14790572 0.79 LPL (0.34) GAACD44JAK2BTKLPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
WO-2024123663-A1 ANTIMICROBIAL COMPOUNDS SRI INTERNATIONAL (US) 2024-06-13 WO disclosed