Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SPR | P35270 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101626 | 0.83 | HTR2A (0.63) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL2993848 | 0.83 | HTR2C (0.63) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL15920450 | 0.80 | HTR2C (0.74) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL14907356 | 0.79 | HTR2C (0.72) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL22953701 | 0.77 | MPO (0.72) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL453066 | 0.76 | TRPV1 (0.67) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL8607176 | 0.75 | HTR2A (0.61) | KDM4EMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28672341 | 0.75 | HTR2C (0.70) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL25076744 | 0.75 | HTR2C (0.65) | HTR2CKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL23630275 | 0.75 | TRPV1 (0.69) | HTR2CKDM4ECYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |