Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25360990 | 0.86 | FURIN (0.40) | ROCK2 | |
| SCHEMBL17312927 | 0.86 | FURIN (0.40) | ROCK2 | |
| SCHEMBL25360995 | 0.86 | FURIN (0.40) | ROCK2 | |
| SCHEMBL24235147 | 0.85 | CA2 (0.37) | CA1CA2KMT2A | |
| SCHEMBL31045340 | 0.85 | CA1 (0.41) | CA1CA2SIRT5KDM4EMAPT | |
| SCHEMBL23798630 | 0.81 | CASP1 (0.38) | GAA | |
| SCHEMBL27143504 | 0.81 | CASP1 (0.38) | GAA | |
| SCHEMBL23071878 | 0.81 | CASP1 (0.38) | GAA | |
| SCHEMBL21163027 | 0.80 | CA1 (0.43) | CA1CA2SIRT5KDM4EMAPT | |
| SCHEMBL29335201 | 0.80 | CA1 (0.45) | CA1CA2SIRT5KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153185-A1 | ANTIBODY-DRUG CONJUGATE CONTAINING BCL-2 FAMILY PROTEOLYSIS AGENT, PREPARATION METHOD THEREFOR, AND USE THEREOF | 苏州宜联生物医药有限公司 | 2024-07-25 | — | — | WO | disclosed |