Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | F13A1 | P00488 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29210589 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL27944339 | 0.85 | PLK4 (0.55) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL328568 | 0.85 | MAPT (1.00) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30616852 | 0.85 | MAPT (1.00) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL28839145 | 0.83 | MAPT (0.97) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Bromide SCHEMBL28839154 | 0.83 | MAPT (0.97) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL29870429 | 0.83 | MAPT (0.97) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL734819 | 0.83 | MAPT (0.78) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Water SCHEMBL1321161 | 0.83 | MAPT (0.97) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Potassium SCHEMBL29870134 | 0.83 | MAPT (0.97) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986264-A | Benzo nitrogen-containing polycyclic derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-07 | — | — | CN | disclosed |