Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | F13A1 | P00488 | 1/20 | 0.64 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.60 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | JAK3 | P52333 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616852 | 0.88 | MAPT (1.00) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL328568 | 0.88 | MAPT (1.00) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| Potassium SCHEMBL29870134 | 0.86 | MAPT (0.97) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28839145 | 0.86 | MAPT (0.97) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL29870429 | 0.86 | MAPT (0.97) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| Water SCHEMBL1321161 | 0.86 | MAPT (0.97) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| Bromide SCHEMBL28839154 | 0.86 | MAPT (0.97) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL20368742 | 0.85 | ALDH1A1 (0.58) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| SCHEMBL15762685 | 0.85 | KDM4E (0.76) | MAPTHSD17B10KDM4EHIF1AALDH1A1 | |
| Acetic Acid SCHEMBL28839867 | 0.85 | MAPT (0.93) | MAPTHSD17B10KDM4EHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387597-A1 | Injectable intraocular microgel as drug delivery system, and hydrogel comprising same | CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR) | 2022-12-08 | — | — | US | disclosed |
| US-20180193522-A1 | INJECTABLE HYDROGELS AND APPLICATIONS THEREOF | LIFECELL CORPORATION | 2018-07-12 | — | — | US | disclosed |
| WO-2018118862-A1 | INJECTABLE HYDROGELS AND APPLICATIONS THEREOF | LIFECELL CORPORATION (US) | 2018-06-28 | — | — | WO | disclosed |
| US-8207262-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2012-06-26 | — | — | US | disclosed |
| US-8137688-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138265-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2012-03-20 | — | — | US | disclosed |
| US-8021350-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20090252700-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-10-08 | — | — | US | disclosed |
| US-20090143766-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090142309-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090042294-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-02-12 | — | — | US | disclosed |
| US-7465766-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-12-16 | — | — | US | disclosed |
| US-7368502-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387597-A1 | Injectable intraocular microgel as drug delivery system, and hydrogel comprising same | CD44, MSN, WEE1 | MAPT 2175/4885HSD17B10 2641/4885KDM4E 3390/4885 |
| US-20090252700-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | CD44, PLOD3, HPSE | MAPT 1440/4885HSD17B10 884/4885KDM4E 3329/4885 |
| US-20090142309-A1 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | PLOD3, IDUA, SYVN1 | MAPT 3995/4885HSD17B10 1990/4885KDM4E 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.