Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | GPR4 | P46093 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983947 | 0.90 | ADORA2A (0.45) | CNR1CNR2GPR4TBK1EPHX2 | |
| SCHEMBL30983856 | 0.90 | CNR1 (0.41) | CNR1CNR2GPR4EPHX2SQOR | |
| SCHEMBL30983846 | 0.89 | CNR1 (0.47) | CNR1CNR2GPR4EPHX2DRD3 | |
| SCHEMBL30983965 | 0.83 | EPHX2 (0.39) | CNR1CNR2GPR4EPHX2DRD3 | |
| SCHEMBL30983874 | 0.82 | GPR4 (0.38) | CNR1CNR2GPR4TBK1EPHX2 | |
| SCHEMBL30983781 | 0.82 | CNR1 (0.39) | CNR1CNR2GPR4PIK3CD | |
| SCHEMBL30983841 | 0.81 | CNR1 (0.41) | CNR1CNR2GPR4EPHX2DRD3 | |
| SCHEMBL30983836 | 0.81 | CNR1 (0.41) | CNR1CNR2GPR4EPHX2DRD3 | |
| SCHEMBL30984010 | 0.80 | CNR1 (0.43) | CNR1CNR2GPR4EPHX2DRD3 | |
| SCHEMBL30984061 | 0.78 | HRH4 (0.48) | GPR4EPHX2DRD3GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |