Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983866 | 0.88 | KDM4E (0.51) | GPR4EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL31269123 | 0.88 | GPR4 (0.51) | GPR4EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL30984069 | 0.88 | GPR119 (0.51) | GPR4EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL31268813 | 0.88 | DRD3 (0.53) | GPR4EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL31269031 | 0.86 | GPR4 (0.47) | GPR4EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL30983940 | 0.86 | GPR4 (0.49) | GPR4EPHX2GPR119DRD3KCNA5 | |
| SCHEMBL3425544 | 0.83 | PDE3B (0.47) | EPHX2GPR119PDE3BPDE3A | |
| SCHEMBL3424112 | 0.83 | GPR119 (0.62) | GPR119 | |
| SCHEMBL1673377 | 0.83 | GPR4 (0.53) | GPR4EPHX2GPR119DRD3DRD2 | |
| SCHEMBL30983957 | 0.82 | CYP4F2 (0.45) | GPR4EPHX2GPR119CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |