Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31626878 | 0.99 | ADORA2A (0.33) | ADORA2AADORA1 | |
| SCHEMBL30983799 | 0.74 | PDPK1 (0.33) | — | |
| SCHEMBL31626948 | 0.72 | — | — | |
| SCHEMBL8565 | 0.67 | ADORA2A (0.58) | ADORA2AADORA1 | |
| SCHEMBL31269071 | 0.66 | LIMK1 (0.33) | — | |
| SCHEMBL31321946 | 0.65 | DGAT1 (0.36) | — | |
| SCHEMBL17289600 | 0.65 | ADORA2A (0.43) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL7290011 | 0.60 | HTR2C (0.49) | ADORA2A | |
| SCHEMBL8342338 | 0.59 | ADORA2A (0.49) | ADORA2AADORA1 | |
| SCHEMBL14347073 | 0.59 | PDPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |