Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984261 | 0.93 | THRB (0.35) | THRBMEN1KMT2ATDP1MAPT | |
| SCHEMBL30984155 | 0.90 | THRB (0.40) | THRBMEN1KMT2ATDP1MAPT | |
| SCHEMBL30984148 | 0.86 | THRB (0.38) | THRBMEN1KMT2ATDP1MAPT | |
| SCHEMBL25035250 | 0.83 | ACHE (0.44) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL30037179 | 0.83 | ACHE (0.44) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL30984328 | 0.83 | THRB (0.41) | THRBMEN1KMT2ATDP1MAPT | |
| SCHEMBL30984280 | 0.82 | WRN (0.49) | THRBMAPTTP53ALDH1A1LMNA | |
| SCHEMBL31713877 | 0.78 | KDM4E (0.44) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL25037080 | 0.76 | WRN (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL30984247 | 0.75 | WRN (0.49) | THRBMAPTTP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153155-A1 | DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都微芯药业有限公司 | 2024-07-25 | — | — | WO | disclosed |