Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985114 | 0.95 | CRBN (0.46) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30984741 | 0.94 | CRBN (0.48) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30985051 | 0.94 | CRBN (0.47) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30984740 | 0.89 | CRBN (0.60) | CRBNDDB1IKZF2 | |
| SCHEMBL30985073 | 0.88 | IKZF2 (0.49) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30985124 | 0.87 | IKZF2 (0.53) | CRBNDDB1IKZF2 | |
| SCHEMBL29986754 | 0.85 | CRBN (0.52) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30984941 | 0.85 | CRBN (0.47) | CRBNDDB1IKZF2MEN1KMT2A | |
| SCHEMBL30985169 | 0.84 | CRBN (0.58) | CRBNDDB1IKZF2 | |
| SCHEMBL30984919 | 0.83 | CRBN (0.61) | CRBNDDB1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |