Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | WIZ | O95785 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985073 | 0.93 | IKZF2 (0.49) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL30985051 | 0.92 | CRBN (0.47) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL30984708 | 0.90 | CRBN (0.47) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL30984941 | 0.90 | CRBN (0.47) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL30985054 | 0.88 | CRBN (0.62) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL29986828 | 0.88 | CRBN (0.66) | CRBNIKZF2ESR1DDB1WIZ | |
| SCHEMBL30984741 | 0.86 | CRBN (0.48) | CRBNIKZF2DDB1MEN1KMT2A | |
| SCHEMBL30984672 | 0.85 | CRBN (0.47) | CRBNIKZF2DDB1MEN1KMT2A | |
| SCHEMBL30942549 | 0.85 | IKZF2 (0.56) | CRBNIKZF2ESR1WIZCSNK1A1 | |
| SCHEMBL27424055 | 0.85 | IKZF2 (0.56) | CRBNIKZF2ESR1WIZCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251224-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2022-12-01 | — | — | WO | disclosed |