Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536683 | 0.85 | GPR119 (0.53) | CYP2C19MEN1KMT2ATSHRNAMPT | |
| SCHEMBL20468940 | 0.81 | CYP11B2 (0.53) | CYP11B2ACACBSCD5HDAC2CYP3A4 | |
| SCHEMBL30263212 | 0.81 | GPR119 (0.49) | CYP11B2ACACBHIF1ASCD5HDAC2 | |
| SCHEMBL24107659 | 0.81 | GPR119 (0.49) | CYP11B2ACACBHIF1ASCD5HDAC2 | |
| SCHEMBL30484800 | 0.80 | CYP11B2 (0.56) | CYP11B2ACACBSCD5HDAC2MEN1 | |
| SCHEMBL25885002 | 0.80 | CYP11B2 (0.56) | CYP11B2ACACBSCD5HDAC2MEN1 | |
| SCHEMBL1639768 | 0.80 | CRBN (0.53) | CYP11B2ACACBCYP3A4CYP2C19KMT2A | |
| SCHEMBL30328685 | 0.80 | CYP11B2 (0.50) | CYP11B2ACACBHIF1ACYP3A4CYP2C19 | |
| SCHEMBL30329041 | 0.79 | CYP11B2 (0.52) | CYP11B2ACACBHIF1ACYP3A4CYP2C19 | |
| SCHEMBL484102 | 0.78 | HIF1A (0.63) | CYP11B2HIF1ACYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |