Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | ITK | Q08881 | 3/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984972 | 0.93 | CRBN (0.60) | CRBNDDB1ARITKIRAK1 | |
| SCHEMBL30984857 | 0.89 | CRBN (0.60) | CRBNDDB1ARITKIL2 | |
| SCHEMBL30985141 | 0.87 | CRBN (0.59) | CRBNDDB1ARITKIRAK1 | |
| SCHEMBL30984986 | 0.86 | CRBN (0.62) | CRBNDDB1ARHPGDS | |
| SCHEMBL30985007 | 0.86 | CRBN (0.62) | CRBNDDB1ARHPGDS | |
| SCHEMBL30984808 | 0.86 | CRBN (0.59) | CRBNDDB1ARITKIRAK1 | |
| SCHEMBL23117865 | 0.85 | CRBN (0.54) | CRBNDDB1ARITKIL2 | |
| SCHEMBL29821993 | 0.85 | CRBN (0.54) | CRBNDDB1ARITKIL2 | |
| SCHEMBL25691033 | 0.85 | CRBN (0.54) | CRBNDDB1ARITKIL2 | |
| SCHEMBL30985039 | 0.84 | CRBN (0.58) | CRBNDDB1ARITKIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |