Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.60 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985141 | 0.94 | CRBN (0.59) | CRBNDDB1ARCDK9ITK | |
| SCHEMBL30984807 | 0.93 | CRBN (0.58) | CRBNDDB1ARCDK9ITK | |
| SCHEMBL30984808 | 0.91 | CRBN (0.59) | CRBNDDB1ARCDK9ITK | |
| SCHEMBL30985039 | 0.90 | CRBN (0.58) | CRBNDDB1ARCDK9ITK | |
| SCHEMBL30984978 | 0.89 | CRBN (0.62) | CRBNDDB1ARCDK9ITK | |
| SCHEMBL30984679 | 0.89 | CRBN (0.58) | CRBNDDB1ARCDK9BTK | |
| SCHEMBL30984986 | 0.88 | CRBN (0.62) | CRBNDDB1AR | |
| SCHEMBL30985007 | 0.88 | CRBN (0.62) | CRBNDDB1AR | |
| SCHEMBL30984874 | 0.86 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL24481028 | 0.86 | CRBN (0.65) | CRBNDDB1ARBTKALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |