Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.62 |
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985007 | 1.00 | CRBN (0.62) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30984990 | 0.96 | CRBN (0.59) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30985238 | 0.95 | CRBN (0.61) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30984882 | 0.91 | CRBN (0.61) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30984670 | 0.89 | CRBN (0.59) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30984972 | 0.88 | CRBN (0.60) | CRBNDDB1AR | |
| SCHEMBL30985040 | 0.88 | CRBN (0.65) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30985055 | 0.88 | CRBN (0.65) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30984679 | 0.87 | CRBN (0.58) | CRBNDDB1ARMEN1KMT2A | |
| SCHEMBL30984807 | 0.86 | CRBN (0.58) | CRBNDDB1ARHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |