Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | WIZ | O95785 | 1/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985120 | 0.95 | CRBN (0.58) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL30984736 | 0.94 | CRBN (0.59) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL30984859 | 0.93 | CRBN (0.56) | CRBNGSPT1 | |
| SCHEMBL30984966 | 0.91 | CRBN (0.56) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL30985009 | 0.89 | CRBN (0.58) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL20234982 | 0.88 | CRBN (0.63) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL29614522 | 0.88 | CRBN (0.63) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL31586353 | 0.87 | CRBN (0.60) | CRBNIKZF2CSNK1A1ESR1WIZ | |
| SCHEMBL30985089 | 0.86 | CRBN (0.54) | CRBNIKZF2CSNK1A1WIZ | |
| SCHEMBL30984838 | 0.86 | CRBN (0.59) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |