SCHEMBL30984859

SCHEMBL30984859

O=C1CCC(N2Cc3ccc(N4CCC5(CCC(CO)CC5)C4)cc3C2=O)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.56
▸ GSPT1 P15170 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30984838 0.94 CRBN (0.59) CRBN
SCHEMBL30984858 0.93 CRBN (0.56) CRBNGSPT1
SCHEMBL30985016 0.91 CRBN (0.56) CRBNGSPT1
SCHEMBL30985048 0.89 CRBN (0.58) CRBNGSPT1
SCHEMBL24046445 0.88 CRBN (0.63) CRBN
SCHEMBL30747130 0.88 CRBN (0.63) CRBN
SCHEMBL26658534 0.88 CRBN (0.63) CRBN
SCHEMBL30646886 0.88 CRBN (0.63) CRBN
SCHEMBL29614668 0.88 CRBN (0.63) CRBN
SCHEMBL26649398 0.88 CRBN (0.63) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146502-A1 WEE1 DEGRADING COMPOUNDS BEIJING NEOX BIOTECH LIMITED (CN) 2024-07-11 — — WO disclosed
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