Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.55 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984956 | 0.93 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL20235033 | 0.92 | CRBN (0.56) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL30984737 | 0.90 | CRBN (0.51) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL30985214 | 0.89 | CRBN (0.52) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL30984866 | 0.88 | CRBN (0.52) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL27313191 | 0.84 | CRBN (0.52) | CRBNIKZF2IKZF1 | |
| SCHEMBL30984768 | 0.84 | CRBN (0.53) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL31025888 | 0.84 | CRBN (0.53) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL20235032 | 0.83 | CRBN (0.49) | CRBNIKZF2IKZF1CSNK1A1DDB1 | |
| SCHEMBL27323900 | 0.83 | CRBN (0.50) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |