SCHEMBL30984956

SCHEMBL30984956

O=C1CCC(N2Cc3ccc(-c4cnn(C5CCNCC5)c4)cc3C2=O)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.55
▸ DDB1 Q16531 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30984869 0.93 CRBN (0.55) CRBNDDB1
SCHEMBL20235033 0.84 CRBN (0.56) CRBN
SCHEMBL30984768 0.84 CRBN (0.53) CRBNDDB1
SCHEMBL30984737 0.83 CRBN (0.51) CRBN
SCHEMBL30985214 0.82 CRBN (0.52) CRBN
SCHEMBL30984866 0.81 CRBN (0.52) CRBN
SCHEMBL27313191 0.79 CRBN (0.52) CRBN
SCHEMBL23565612 0.78 CRBN (0.69) CRBN
SCHEMBL29791157 0.78 CRBN (0.71) CRBNDDB1
SCHEMBL23534326 0.78 CRBN (0.71) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146502-A1 WEE1 DEGRADING COMPOUNDS BEIJING NEOX BIOTECH LIMITED (CN) 2024-07-11 — — WO disclosed
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