Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159547 | 0.89 | MAPT (0.51) | NR1H2GPR119KDM4EMAPTTHRB | |
| SCHEMBL30021635 | 0.89 | MAPT (0.51) | NR1H2GPR119KDM4EMAPTTHRB | |
| SCHEMBL30984706 | 0.83 | GPR119 (0.49) | NR1H2GPR119MAPTNAMPTALDH1A1 | |
| SCHEMBL30962613 | 0.82 | NR1H2 (0.49) | NR1H2GPR119KDM4EMAPTTHRB | |
| SCHEMBL30962762 | 0.81 | NR1H2 (0.48) | NR1H2KDM4EALDH1A1 | |
| SCHEMBL3815448 | 0.80 | MAPT (0.52) | NR1H2GPR119KDM4EMAPTTHRB | |
| SCHEMBL23868014 | 0.79 | MGLL (0.53) | GPR119MAPTACACBNAMPT | |
| SCHEMBL31443726 | 0.77 | NR1H2 (0.54) | NR1H2GPR119KDM4EMAPTTHRB | |
| SCHEMBL31549191 | 0.76 | NR1H2 (0.53) | NR1H2GPR119HDAC2HDAC1ACACB | |
| SCHEMBL24629830 | 0.76 | STS (0.50) | NR1H2GPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |