Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984702 | 0.92 | SIRT6 (0.50) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL30985131 | 0.89 | SIRT6 (0.56) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL30984879 | 0.86 | SIRT6 (0.57) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL21526328 | 0.85 | SIRT6 (0.64) | SIRT6ADRB1MAPTMEN1KMT2A | |
| SCHEMBL30817337 | 0.84 | SIRT6 (0.68) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL30985102 | 0.82 | SIRT6 (0.56) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL30984921 | 0.82 | ADRB1 (0.46) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL30985139 | 0.81 | SIRT6 (0.54) | SIRT6HRH3ADRB1MAPTMEN1 | |
| SCHEMBL30984723 | 0.80 | SIRT6 (0.56) | SIRT6HRH3ADRB1SIGMAR1MAPT | |
| SCHEMBL28241 | 0.80 | KMT2A (0.60) | SIRT6HRH3ADRB1SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |