Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | FES | P07332 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984852 | 0.87 | JAK2 (0.35) | SYKCHRM4JAK2ALDH1A1HSD17B10 | |
| SCHEMBL30984928 | 0.79 | HSD17B10 (0.39) | ALDH1A1HSD17B10PARP1ROCK2IP6K1 | |
| SCHEMBL30985167 | 0.79 | SOS1 (0.39) | HSD17B10PARP1ROCK2IP6K1PDE3B | |
| SCHEMBL30984964 | 0.78 | CYP3A4 (0.36) | SYKCHRM4JAK2ALDH1A1HSD17B10 | |
| SCHEMBL25937317 | 0.78 | HSD17B10 (0.53) | SYKALDH1A1HSD17B10PARP1PRKCI | |
| SCHEMBL30985068 | 0.73 | CRBN (0.44) | — | |
| SCHEMBL25141632 | 0.71 | MAPT (0.48) | ALDH1A1PARP1CYP3A4ROCK2MAPT | |
| SCHEMBL30544653 | 0.71 | TIPARP (0.45) | ALDH1A1HSD17B10PARP1PRKCIPDE4B | |
| SCHEMBL31542352 | 0.69 | EGFR (0.39) | — | |
| SCHEMBL25134014 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |